WEKO3
アイテム
{"_buckets": {"deposit": "a77eda13-e577-4c41-af7d-e9f13421bfb8"}, "_deposit": {"created_by": 5, "id": "1583", "owners": [5], "pid": {"revision_id": 0, "type": "depid", "value": "1583"}, "status": "published"}, "_oai": {"id": "oai:iwatemed.repo.nii.ac.jp:00001583", "sets": ["128", "392"]}, "author_link": ["5549", "5547", "5548"], "item_2_biblio_info_14": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2008-12-19", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "147", "bibliographicPageStart": "137", "bibliographicVolumeNumber": "33", "bibliographic_titles": [{"bibliographic_title": "岩手医科大学歯学雑誌"}, {"bibliographic_title": "Dental journal of Iwate Medical University", "bibliographic_titleLang": "en"}]}]}, "item_2_creator_6": {"attribute_name": "著者名(日)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "原賀, 裕"}], "nameIdentifiers": [{"nameIdentifier": "5547", "nameIdentifierScheme": "WEKO"}]}]}, "item_2_creator_7": {"attribute_name": "著者名よみ", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "ハラガ, ヒロシ"}], "nameIdentifiers": [{"nameIdentifier": "5548", "nameIdentifierScheme": "WEKO"}]}]}, "item_2_creator_8": {"attribute_name": "著者名(英)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "HARAGA, Hiroshi", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "5549", "nameIdentifierScheme": "WEKO"}]}]}, "item_2_description_1": {"attribute_name": "ページ属性", "attribute_value_mlt": [{"subitem_description": "P(論文)", "subitem_description_type": "Other"}]}, "item_2_description_12": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "Porphyromonas endodontalis, a black-pigmented anaerobe, is a predominant pathogen of human periapical periodontitis. In contrast to P. gingivalis, a major pathogen of chronic periodontitis, the pathogenic factor(s) of P. endodontalis has been poorly characterized. In this study, the protease activities in the P. endodontalis extracellular fraction were examined using various MCA polypeptides. The results indicated that the extracellular fraction had a spectrum of proteolytic activities distinct from that of P. gingivalis, and that Ala- and Asp-specific proteolytic activities were substantially present in the extracellular fraction. Then, the extracellular fraction was subjected to ion-exchange chromatography. The Asp-specific proteolytic activity was eluted from a DEAE-Sephacel column separately from the Ala-specific one, and the fraction was designated as the DEAE-purified fraction. The further experiments on the effects of protease inhibitors also suggested that the DEAE-purified fraction contains a novel Asp-specific dipeptidylpeptidase. It was confirmed by the MALDI-TOF MS analyses on the substrate preference using neuromedin B and a series of synthetic neuromedin B analogues. Taken together, P. endodontalis possesses a novel Asp-specific dipeptidylpeptidase in the extracellular fraction, which could be involved in an important etiologic process in the specific pathological potential of this organisms in human periapical periodontitis.", "subitem_description_type": "Other"}]}, "item_2_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00017474", "subitem_source_identifier_type": "NCID"}]}, "item_2_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Oral Microbiology, School of Dentistry, Iwate Medical University"}]}, "item_2_text_2": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_text_value": "研究"}]}, "item_2_text_3": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Original"}]}, "item_2_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "岩手医科大学歯学部口腔微生物学講座"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2008-12-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00005130303.pdf", "filesize": [{"value": "849.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Creative Commons : 表示 - 非営利 - 改変禁止", "licensetype": "license_free", "mimetype": "application/pdf", "size": 849400.0, "url": {"label": "KJ00005130303", "url": "https://iwatemed.repo.nii.ac.jp/record/1583/files/KJ00005130303.pdf"}, "version_id": "f66c4ed2-d78a-4a12-ad17-cdd1061668a3"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Porphyromonas endodontalis", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "protease", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Asp-specific dipeptidylpeptidase", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Porphyromonas endodontalisが産生する新規のアスパラギン酸特異的ジペプチジルペプチダーゼの解析", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Porphyromonas endodontalisが産生する新規のアスパラギン酸特異的ジペプチジルペプチダーゼの解析"}, {"subitem_title": "A novel Asp-specific dipeptidylpeptidase produced from Porphyromonas endodontalis", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "5", "path": ["128", "392"], "permalink_uri": "https://iwatemed.repo.nii.ac.jp/records/1583", "pubdate": {"attribute_name": "公開日", "attribute_value": "2008-12-19"}, "publish_date": "2008-12-19", "publish_status": "0", "recid": "1583", "relation": {}, "relation_version_is_last": true, "title": ["Porphyromonas endodontalisが産生する新規のアスパラギン酸特異的ジペプチジルペプチダーゼの解析"], "weko_shared_id": 5}
Porphyromonas endodontalisが産生する新規のアスパラギン酸特異的ジペプチジルペプチダーゼの解析
https://iwatemed.repo.nii.ac.jp/records/1583
https://iwatemed.repo.nii.ac.jp/records/1583b0b3ce28-cb27-4ef3-bc8f-19ebd97ead64
名前 / ファイル | ライセンス | アクション |
---|---|---|
KJ00005130303 (849.4 kB)
|
Creative Commons : 表示 - 非営利 - 改変禁止
|
Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2008-12-19 | |||||
タイトル | ||||||
タイトル | Porphyromonas endodontalisが産生する新規のアスパラギン酸特異的ジペプチジルペプチダーゼの解析 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | A novel Asp-specific dipeptidylpeptidase produced from Porphyromonas endodontalis | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
記事種別(日) | ||||||
研究 | ||||||
記事種別(英) | ||||||
en | ||||||
Original | ||||||
著者名(日) |
原賀, 裕
× 原賀, 裕 |
|||||
著者名よみ |
ハラガ, ヒロシ
× ハラガ, ヒロシ |
|||||
雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00017474 | |||||
書誌情報 |
岩手医科大学歯学雑誌 en : Dental journal of Iwate Medical University 巻 33, 号 3, p. 137-147, 発行日 2008-12-19 |