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The aim of this study was to examine the effects of POs on remineralization of caries-like lesions in enamel in vitro. Bovine enamel slabs were demineralized in a 0.1 M lactic acid gel (pH 5) at 37℃ for 3 w, and subsequently remineralized in a mineral solution (20 mM Hepes, 1.5 mM CaCl_2, 0.9 mM KH_2PO_4, pH 7 ) with addition of 2 ppm F^- as NaF or various concentrations of POs (0.07-4%) at 37℃ for 7 d. The mineral distributions in enamel were quantified by transversal microradiography. The mineral loss values (ΔZ, vol%・μm) in the samples treated by the mineral solution containing 0.07-0.2% POs were significantly lower (p\u003c0.001) compared with demineralized enamel samples and were statistically similar to that in the samples in 2 ppm F group. Remineralization rates of the samples in the POs groups were inversely correlated with the logarithmic values of POs concentration with a significant correlation coefficient (r=0.99, p\u003c0.0001). The present results suggested that POs may be a novel and unique substance to enhance enamel remineralization, and could be utilized for caries prevention by nutritional approach.", "subitem_description_type": "Other"}]}, "item_2_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00017474", "subitem_source_identifier_type": "NCID"}]}, "item_2_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Preventive Dentistry, School of Dentistry, Iwate Medical University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Preventive Dentistry, School of Dentistry, Iwate Medical University"}, {"subitem_text_language": "en", "subitem_text_value": "Biochemical Research Laboratory, Ezaki Glico Co., Ltd."}, {"subitem_text_language": "en", "subitem_text_value": "Department of Preventive Dentistry, School of Dentistry, Iwate Medical University"}]}, "item_2_text_2": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_text_value": "研究"}]}, "item_2_text_3": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Original"}]}, "item_2_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "岩手医科大学歯学部予防歯科学講座"}, {"subitem_text_value": "岩手医科大学歯学部予防歯科学講座"}, {"subitem_text_value": "江崎グリコ(株)生物化学研究所"}, {"subitem_text_value": "岩手医科大学歯学部予防歯科学講座"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2002-12-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00002373616.pdf", "filesize": [{"value": "432.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Creative Commons : 表示 - 非営利 - 改変禁止", "licensetype": "license_free", "mimetype": "application/pdf", "size": 432400.0, "url": {"label": "KJ00002373616", "url": "https://iwatemed.repo.nii.ac.jp/record/1653/files/KJ00002373616.pdf"}, "version_id": "6ed7d157-b559-4f7a-951f-96cc16dbf12b"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "リン酸化オリゴ糖(POs)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "再石灰化", "subitem_subject_scheme": "Other"}, {"subitem_subject": "エナメル質", "subitem_subject_scheme": "Other"}, {"subitem_subject": "マイクロラジオグラフィ", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Phosphoryl Oligosaccharides (POs)", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Remineralization", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Enamel", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Microradiography", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "エナメル質齲蝕病巣のin vitro再石灰化におよぼすリン酸化オリゴ糖(POs)の効果", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "エナメル質齲蝕病巣のin vitro再石灰化におよぼすリン酸化オリゴ糖(POs)の効果"}, {"subitem_title": "Effects of Phosphoryl-Oligosaccharides (POs) on Remineralization of Enamel Lesions in vitro", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "5", "path": ["111", "397"], "permalink_uri": "https://iwatemed.repo.nii.ac.jp/records/1653", "pubdate": {"attribute_name": "公開日", "attribute_value": "2002-12-24"}, "publish_date": "2002-12-24", "publish_status": "0", "recid": "1653", "relation": {}, "relation_version_is_last": true, "title": ["エナメル質齲蝕病巣のin vitro再石灰化におよぼすリン酸化オリゴ糖(POs)の効果"], "weko_shared_id": 5}
エナメル質齲蝕病巣のin vitro再石灰化におよぼすリン酸化オリゴ糖(POs)の効果
https://iwatemed.repo.nii.ac.jp/records/1653
https://iwatemed.repo.nii.ac.jp/records/16533aafcd8d-6036-430f-be4f-8f61a86c3d5d
名前 / ファイル | ライセンス | アクション |
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KJ00002373616 (432.4 kB)
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Creative Commons : 表示 - 非営利 - 改変禁止
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
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公開日 | 2002-12-24 | |||||
タイトル | ||||||
タイトル | エナメル質齲蝕病巣のin vitro再石灰化におよぼすリン酸化オリゴ糖(POs)の効果 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effects of Phosphoryl-Oligosaccharides (POs) on Remineralization of Enamel Lesions in vitro | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
記事種別(日) | ||||||
研究 | ||||||
記事種別(英) | ||||||
en | ||||||
Original | ||||||
著者名(日) |
稲葉, 大輔
× 稲葉, 大輔× 南, 健太郎× 釜阪, 寛× 米満, 正美 |
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著者名よみ |
イナバ,ダイスケ,ミナミ,ケンタロウ,カマサカ,ヒロシ,ヨネミツ,マサミ
× イナバ,ダイスケ,ミナミ,ケンタロウ,カマサカ,ヒロシ,ヨネミツ,マサミ |
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雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00017474 | |||||
書誌情報 |
岩手医科大学歯学雑誌 en : Dental journal of Iwate Medical University 巻 27, 号 3, p. 197-202, 発行日 2002-12-24 |