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The peripheral test stimulus (a single rectangular pulse of 2.0 msec in duration) was applied to the facial skin in the receptive field of nociceptive neurons, and the ipsilateral amygdaloid conditioning stimuli to the recording site were trains of 33 pulses (0.5 msec in duration, 100-300 μA) delivered at 330Hz. Fifty-six wide dynamic range (WDR) neurons and 15 nociceptive specifc (NS) neurons were recorded WDR neurons were distributed in the superficial layer of the caudal nucleus and diffusely throughout the reticular subnucleus, whereas most of the NS neurons were distributed in the dorsal part of the reticular subnucleus The conditioning stimulation in the central nucleus, basomedial and basolateral nuclei markedly inhibited the activities in 8 of 8 nociceptive neurons (3 WDR and 5 NS neurons) The inhibitory effect was 73 6±12 8% (mean±S.D) at maximum Naloxone (2mg/kg, iv.), opioid receptor antagonist, did not exert an influence on the amygdaloid inhibitory effect (n=4) The present results suggest that the amygdaloid nucleus inhibits the ascending nociceptive information at the 2nd order neurons through a receptor other than the opioid receptor. It has been known that the amygdaloid nucleus is a key structure for mediating stress responses Therefore, the amygdaloid antmociceptive effect may provide one of the neurophysiological bases for stress-induced analgesia (SIA), especially non-opioid type SIA.", "subitem_description_type": "Other"}]}, "item_2_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00017474", "subitem_source_identifier_type": "NCID"}]}, "item_2_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Orthodontics, School of Dentistry, Iwate Medical University"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Oral Physiology, School of Dentistry, Iwate Medical University"}]}, "item_2_text_2": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_text_value": "研究"}]}, "item_2_text_3": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Oliginal"}]}, "item_2_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "岩手医科大学歯学部歯科矯正学講座"}, {"subitem_text_value": "岩手医科大学歯学部口腔生理学講座"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2004-12-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00002373793.pdf", "filesize": [{"value": "1.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Creative Commons : 表示 - 非営利 - 改変禁止", "licensetype": "license_free", "mimetype": "application/pdf", "size": 1200000.0, "url": {"label": "KJ00002373793", "url": "https://iwatemed.repo.nii.ac.jp/record/1829/files/KJ00002373793.pdf"}, "version_id": "8d23c628-81f8-464d-ae1e-bf1de45b1d30"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "amygdala, antmociception", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "conditioning stimulation", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "caudal nucleus", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "reticular subnulei", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "stress-induced analgesia", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "ラット延髄後角の侵害受容細胞に対する扁桃体条件刺激の抑制効果にオピオイド受容体が関与するか?", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "ラット延髄後角の侵害受容細胞に対する扁桃体条件刺激の抑制効果にオピオイド受容体が関与するか?"}, {"subitem_title": "Is the opioid receptor involved in the inhibitory effect of amygdaloid conditioning stimulation on the nociceptive neurons in the medullary dorsal horn of the rat?", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "5", "path": ["116", "405"], "permalink_uri": "https://iwatemed.repo.nii.ac.jp/records/1829", "pubdate": {"attribute_name": "公開日", "attribute_value": "2004-12-20"}, "publish_date": "2004-12-20", "publish_status": "0", "recid": "1829", "relation": {}, "relation_version_is_last": true, "title": ["ラット延髄後角の侵害受容細胞に対する扁桃体条件刺激の抑制効果にオピオイド受容体が関与するか?"], "weko_shared_id": 5}
ラット延髄後角の侵害受容細胞に対する扁桃体条件刺激の抑制効果にオピオイド受容体が関与するか?
https://iwatemed.repo.nii.ac.jp/records/1829
https://iwatemed.repo.nii.ac.jp/records/182952893bcb-72e4-4c95-a9b5-6f2a52d25ee8
名前 / ファイル | ライセンス | アクション |
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KJ00002373793 (1.2 MB)
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Creative Commons : 表示 - 非営利 - 改変禁止
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
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公開日 | 2004-12-20 | |||||
タイトル | ||||||
タイトル | ラット延髄後角の侵害受容細胞に対する扁桃体条件刺激の抑制効果にオピオイド受容体が関与するか? | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Is the opioid receptor involved in the inhibitory effect of amygdaloid conditioning stimulation on the nociceptive neurons in the medullary dorsal horn of the rat? | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
記事種別(日) | ||||||
研究 | ||||||
記事種別(英) | ||||||
en | ||||||
Oliginal | ||||||
著者名(日) |
坂東, 三史
× 坂東, 三史× 松本, 範雄 |
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著者名よみ |
バンドウ, サンシ
× バンドウ, サンシ× マツモト, ノリオ |
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雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00017474 | |||||
書誌情報 |
岩手医科大学歯学雑誌 en : Dental journal of Iwate Medical University 巻 29, 号 3, p. 224-235, 発行日 2004-12-20 |