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In this research, the memory was investigated after auditory memory loads in order to understand the amnesia effect and recovery in the intravenous sedation by Dexmedetomidine hydrochloride (DEX). Moreover, the relations between memory and clinical sedation levels (OAA/S Scale) or BIS values were investigated to judge the recovery of memory. Thirty-five volunteers were divided into a thirty persons\u0027 DEX administration group and a five persons\u0027 control group. As control in the DEX administration group, five auditory memory subjects were given from headphones at 15 seconds before DEX administration, so that the subjects might repeat and memorize them. According to the recommendation method, DEX was continuously prescribed in maintenance doses (0.4μg/kg/hr) following in initial dose (6μg/kg/hr) for 10 minutes. The auditory memory tasks were given 3 times every 5 minutes after 3 minutes from the maintenance administration start, and a further 12 times every 10 minutes after the DEX administration stop. After awaking from sedation, the names of all the memorized subjects were written out. Throughout research, blood pressure, heart rate, SpO_2, and BIS values were measured and recorded. Furthermore, in the control group, saline was prescribed for the patient instead of DEX, and set to the same schedule. As results, the rate of the memory decreased significantly by DEX, and was maintained falling even after the DEX administration stop. The rate of the memory recovered at last to a control value and had no significant difference from it 120 minutes after an administration stop. Moreover, we found out the relationship among OAA/S Scale, the BIS value, and the rate of the memory. As a conclusion, the results suggest that recovery of the memory under intravenous sedation with DEX needs 2 hours or more after the administration stop, and OAA/S Scale and the BIS value would be clinical indexes to judge effect and recovery of the amnesia. Therefore, in order to prevent a lapse of memory of notes etc., it is important to explain them in advance, to explain after 2 hours or more passes at BIS value over 81 and checking sufficient recovery, or to show them by a document.", "subitem_description_type": "Other"}]}, "item_2_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00017474", "subitem_source_identifier_type": "NCID"}]}, "item_2_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Division of Dental Anesthesiology Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University"}]}, "item_2_text_2": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_text_value": "研究"}]}, "item_2_text_3": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Original"}]}, "item_2_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "岩手医科大学歯学部口腔外科学講座歯科麻酔学分野"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2010-04-23"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00006253146.pdf", "filesize": [{"value": "848.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Creative Commons : 表示 - 非営利 - 改変禁止", "licensetype": "license_free", "mimetype": "application/pdf", "size": 848400.0, "url": {"label": "KJ00006253146", "url": "https://iwatemed.repo.nii.ac.jp/record/1928/files/KJ00006253146.pdf"}, "version_id": "0359bacd-cbf9-458c-8fb0-0e77a31b5084"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "iv sedation", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Dexmedetomidine hydrochloride", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "amnesia effect", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "塩酸デクスメデトミジンによる静脈内鎮静法が聴覚性記憶に及ぼす影響", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "塩酸デクスメデトミジンによる静脈内鎮静法が聴覚性記憶に及ぼす影響"}, {"subitem_title": "Effect on Auditory Memory by Intravenous Psychosedation with Dexmedetomidine Hydrochloride", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "5", "path": ["118", "461"], "permalink_uri": "https://iwatemed.repo.nii.ac.jp/records/1928", "pubdate": {"attribute_name": "公開日", "attribute_value": "2010-04-23"}, "publish_date": "2010-04-23", "publish_status": "0", "recid": "1928", "relation": {}, "relation_version_is_last": true, "title": ["塩酸デクスメデトミジンによる静脈内鎮静法が聴覚性記憶に及ぼす影響"], "weko_shared_id": 5}
塩酸デクスメデトミジンによる静脈内鎮静法が聴覚性記憶に及ぼす影響
https://iwatemed.repo.nii.ac.jp/records/1928
https://iwatemed.repo.nii.ac.jp/records/1928cf2c1a08-7e85-4f8e-82c0-91ff21deda67
名前 / ファイル | ライセンス | アクション |
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KJ00006253146 (848.4 kB)
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Creative Commons : 表示 - 非営利 - 改変禁止
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-04-23 | |||||
タイトル | ||||||
タイトル | 塩酸デクスメデトミジンによる静脈内鎮静法が聴覚性記憶に及ぼす影響 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Effect on Auditory Memory by Intravenous Psychosedation with Dexmedetomidine Hydrochloride | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
記事種別(日) | ||||||
研究 | ||||||
記事種別(英) | ||||||
en | ||||||
Original | ||||||
著者名(日) |
村上, 加奈
× 村上, 加奈 |
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著者名よみ |
ムラカミ, カナ
× ムラカミ, カナ |
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雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00017474 | |||||
書誌情報 |
岩手医科大学歯学雑誌 en : Dental journal of Iwate Medical University 巻 35, 号 1, p. 10-19, 発行日 2010-04-23 |