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2(S-LPS)のPS画分では全く出血壊死を惹起しなかった。3)合成リピドAの506の活性はR-LPS,天然リピドAと同等か,それ以下の活性を示したが,406はかなり活性が弱かった。4)C3H/HeNマウスはddYマウスと同等の反応を示したが,C3H/HeJマウスでは出血壊死反応を惹起することはできなかった。5)血小板活性化因子(PAF)による皮膚反応ではddY,C3H/HeJともに出血壊死を惹起しC3H/HeJマウスは,かなり強い細胞毒性を示した。2)マウス組織因子産性:1)LPS応答性はddYマウス,C3H/HeNマウス,の順によく,C3H/HeJマウスでは組織因子の産生が見られなかった。2)合成リピドAの406と506と同程度の活性を示した。3)0.1μM,1.0μMのPAF刺激では用量依存性が認められたが,10μMでは組織因子産生が認められなかった", "subitem_description_type": "Abstract"}]}, "item_10002_heading_23": {"attribute_name": "見出し", "attribute_value_mlt": [{"subitem_heading_banner_headline": "歯学部 統合基礎講座", "subitem_heading_headline": "口腔外科 微生物(感染)", "subitem_heading_language": "ja"}]}, "item_10002_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "岩手医科大学歯学会"}]}, "item_10002_rights_15": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "rights:岩手医科大学歯学会 "}, {"subitem_rights": "rights:本文データは学協会の許諾に基づきCiNiiから複製したものである "}]}, "item_10002_source_id_9": {"attribute_name": "ISSN", 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内毒素性リポ多糖の生物活性 : in vivoでのマウス皮膚反応および in vitroでのマクロファージからの組織因子産生
https://iwatemed.repo.nii.ac.jp/records/3125
https://iwatemed.repo.nii.ac.jp/records/31259863f0d5-caf3-47c9-9d0e-085e90016209
名前 / ファイル | ライセンス | アクション |
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A021810051 (1.5 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2014-05-20 | |||||
タイトル | ||||||
タイトル | 内毒素性リポ多糖の生物活性 : in vivoでのマウス皮膚反応および in vitroでのマクロファージからの組織因子産生 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Biological activities of bacterial lipopolysaccharides : skin reaction in mice in vivo and production of tissue factor by macrophages in vitro. | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
石川, 義人
× 石川, 義人× ISHIKAWA, Yoshihito |
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書誌情報 |
岩手医科大学歯学雑誌 en : Dental journal of Iwate Medical University 巻 18, 号 1, p. 51-66, 発行日 1993-04 |
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出版者 | ||||||
出版者 | 岩手医科大学歯学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0385-1311 | |||||
権利 | ||||||
権利情報 | rights:岩手医科大学歯学会 | |||||
権利 | ||||||
権利情報 | rights:本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
見出し | ||||||
大見出し | 歯学部 統合基礎講座 | |||||
小見出し | 口腔外科 微生物(感染) | |||||
言語 | ja |