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In this study, lymphatic architecture and distribution beneath the buccal mucosa of mice were investigated using enzymatic histochemical staining and analysis of the three-dimensional lymphatic architecture using a new 3D reconstruction method. Using the obtained histological image, buccal mucosa was vertically divided into three areas including the upper area from corresponding buccal mucosa to occlusal plane (U), corresponding buccal mucosa to occlusal plane (O) and lower area from corresponding buccal mucosa to occlusal plane (L) areas. Anteroposteriorly, buccal mucosa was divided into four areas comprising the corresponding buccal mucosa to incisor (I), corresponding buccal mucosa to edentulous area (E), corresponding buccal mucosa to molar (M) and fauces area of buccal mucosa (F) areas. Network formation of the lymphatic vessels was observed subepithelially at the buccal mucosa. The networks of the lymphatic vessels were finer than the blood vessels. The precollecting lymphatics heading to the suprafascial collecting lymphatics right below the mucosa was observed on O area. Entering short connective tissue papillae, blind-ends were observed most on LM and OM areas followed by LE and OF areas. It is suggested that the thickness of cornified layers in mucosal epithelium and the entire thickness of the epithelial layers has an effect on drug penetration. In addition to that, UM area is considered to be an effective area to place drugs that require instantaneous effects in terms of penetration. Our results also suggested that OM area is an effective place for drugs with high molecular weight.", "subitem_description_type": "Other"}]}, "item_2_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00017474", "subitem_source_identifier_type": "NCID"}]}, "item_2_text_10": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "First Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University"}, {"subitem_text_language": "en", "subitem_text_value": "First Department of Oral Anatomy, School of Dentistry, Iwate Medical University"}]}, "item_2_text_2": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_text_value": "研究"}]}, "item_2_text_3": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Original"}]}, "item_2_text_9": {"attribute_name": "著者所属(日)", "attribute_value_mlt": [{"subitem_text_value": "岩手医科大学歯学部口腔外科学第一講座"}, {"subitem_text_value": "岩手医科大学歯学部口腔解剖学第一講座"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2009-04-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00005578303.pdf", "filesize": [{"value": "19.8 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensefree": "Creative Commons : 表示 - 非営利 - 改変禁止", "licensetype": "license_free", "mimetype": "application/pdf", "size": 19800000.0, "url": {"label": "KJ00005578303", "url": "https://iwatemed.repo.nii.ac.jp/record/1859/files/KJ00005578303.pdf"}, "version_id": "d131fbc0-905e-4e0e-abc0-19780acd27ad"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "lymphatic architecture", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "distribution", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "buccal mucosa", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "頬粘膜下リンパ管の構築と分布量", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "頬粘膜下リンパ管の構築と分布量"}, {"subitem_title": "Lymphatic architecture and distribution beneath the buccal mucosa", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "5", "path": ["119", "457"], "permalink_uri": "https://iwatemed.repo.nii.ac.jp/records/1859", "pubdate": {"attribute_name": "公開日", "attribute_value": "2009-04-24"}, "publish_date": "2009-04-24", "publish_status": "0", "recid": "1859", "relation": {}, "relation_version_is_last": true, "title": ["頬粘膜下リンパ管の構築と分布量"], "weko_shared_id": 5}
頬粘膜下リンパ管の構築と分布量
https://iwatemed.repo.nii.ac.jp/records/1859
https://iwatemed.repo.nii.ac.jp/records/18594cb2714e-5b9c-4208-ac2e-a9f19e40e0e4
名前 / ファイル | ライセンス | アクション |
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KJ00005578303 (19.8 MB)
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Creative Commons : 表示 - 非営利 - 改変禁止
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Item type | 紀要論文(ELS) / Departmental Bulletin Paper(1) | |||||
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公開日 | 2009-04-24 | |||||
タイトル | ||||||
タイトル | 頬粘膜下リンパ管の構築と分布量 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Lymphatic architecture and distribution beneath the buccal mucosa | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
記事種別(日) | ||||||
研究 | ||||||
記事種別(英) | ||||||
en | ||||||
Original | ||||||
著者名(日) |
佐藤, 大
× 佐藤, 大× 藤村, 朗 |
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著者名よみ |
サトウ, ユタカ
× サトウ, ユタカ× フジムラ, アキラ |
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雑誌書誌ID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00017474 | |||||
書誌情報 |
岩手医科大学歯学雑誌 en : Dental journal of Iwate Medical University 巻 34, 号 1, p. 7-17, 発行日 2009-04-24 |